You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.
However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.
Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.
Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.
Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.
Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:
Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.
Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.
Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.
The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.
In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.
Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.
So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.
However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.
Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.
Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.
Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.
We’d generally recommend trying Second Nature’s before considering a weight-loss jab.
Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.
At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.
In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.
Second Nature was more than twice as effective at supporting weight loss than the other four providers.
However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.
Second Nature has now narrowed down its criteria to help you.Sold and Supplied by Healthylife Pharmacy
This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.
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Healthylife Product InformationSpecies general packagingSpecies 12013151Country of Origin no guaranteedHealthylife Product InformationHealthylife Brand and GenericSpecies general packagingMedicine on speakerphone or video call24/1021This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently-profitactory. It is produced by Bazaarvoice. Healthylife provides general product information including nutritional information, country of origin and product packaging for your convenience. This information is intended as a guide only, but it is ultimately provided to: Healthylife Product InformationHealthylife Patient Information leaflet
Healthylife sg is produced by Healthylife Pharmacy, an independently-profitactory.
Healthylife Product InformationSpecies general packagingSpecies 12013151Country of origin no guaranteedIt is produced by Healthylife Pharmacy, an independently-profitactory.
Dietary fats are large molecules that need to be broken down before they can be absorbed into the body. They are broken down by enzymes called lipases. That is, lipases play an important role in the digestion of dietary fat. When taken with a meal, Xenical interferes with the activity of these enzymes. This allows about 30% of the fat eaten in the meal to pass through the gut undigested. Therefore, your body cannot store these excess calories as fatty tissue or use them as a source of energy. This helps you to reduce your weight by burning up fat that you are already carrying, maintain your lower weight and minimise any weight regain. Losing even small amounts of weight and keeping it off produces additional health benefits for you, especially when you are at risk for other diseases such as heart disease and diabetes. Xenical can also help to improve risk factors, such as high blood pressure, high cholesterol and high blood sugar. If these are not treated, they could lead to other diseases such as hypertension and diabetes. Xenical should be taken in conjunction with a well-balanced calorie-controlled diet and other appropriate measures such as exercise.Active Ingredients:Xenical does not contain sucrose, gluten, tartrazine or any other azo dyes. Active ingredient - orlistat each Xenical capsule contains 120 mg orlistatInactive ingredients
DirectionsTake 1 capsule with each of the 3 main meals per day. It can be taken during the meal or up to 1 hour after the meal is consumed.Warnings & Disclaimers
*** Please note that this product is a Scheduled Medicine in Western Australia. In order to ensure this product is appropriate and safe for you to use, we would appreciate it if you could respond to the following questions for us.
Who is this product for (Age and gender)?
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I have been using Xenical for over a decade. My weight has not reduced significantly over the last few years. I am over 50 and have very healthy body hair. I use it to manage my cholesterol and my bowel movements are very good. I am fit and healthy, and satisfied with how things have gone. I have been using this medication for 3 years now and I am very satisfied with how things are. I am a healthy man with a heavy work history and a great understanding of what I am subjected to in life. I have no health conditions and am looking for simple, non-pharmacy reasons for using this medication. Would you like to add a comment?Orlistat 120mg Capsule
Contains the active substance orlistat, which is an active substance in the body that prevents the body from absorbing or from suppressing food intake. Orlistat 120mg Capsule is the active ingredient in a combination drug that is used for the treatment of weight loss, obesity, and type 2 diabetes. It works by blocking the absorption of fat from the gastrointestinal tract, and the amount of fat from the body, and this helps to lower blood pressure and lower the amount of calories that are absorbed. The drug also helps to control pain and inflammation of the lower back and muscles. Orlistat 120mg Capsule is a weight-loss drug that is used in combination with a healthy diet and exercise program.
ContainsThe active substance orlistatin the capsule
Dosage
The recommended dosage of Orlistat 120mg Capsule is 120 mg per day. In case of overdose, seek immediate medical attention. Orlistat 120mg Capsule is prescribed to reduce the side effects of the drug and aid in weight loss and reduction of excess weight. It works by preventing the action of fat in the body which is absorbed by the body. Orlistat 120mg Capsule is available in 120mg strength. Do not use more than the recommended dose.
Side Effects
Orlistat 120mg Capsule may cause some side effects, but these are usually mild and do not require medical attention. These are common side effects of Orlistat 120mg Capsule that can affect more than one person. The main side effects of Orlistat 120mg Capsule are:
Precautions
Avoid taking the Orlistat 120mg Capsule if you are allergic to orlistat or if you are pregnant or breastfeeding. Do not use the drug if you have a history of liver problems, kidney disorders, or a history of kidney problems. The drug should be taken with a full glass of water and it must not be crushed, chewed, or broken. If you have been diagnosed with obesity and overweight, your doctor may prescribe a weight-loss program. Orlistat 120mg Capsule is a prescription drug. Do not use the drug if you have taken a drug that you are allergic to, or if you have ever had a heart attack, stroke, heart disease, or angina.
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